Reconstituting the Reverse Cholesterol Transport Pathway

LipimetiX is focused on the cost-efficient development of its technology through a virtual company structure under the leadership of experienced scientists and biotech business executives, through a partnership between Benu BioPharma and Capstone Therapeutics. >> Read More

The Apo E mimetics were developed through the intimate knowledge of structure and function of the amphipathic helix in Apolipoproteins.
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Capstone Therapeutics Announces Initiation of Dosing for AEM-28 Phase 1b/2a Human Clinical Trial in Refractory Hypercholesterolemic Subjects
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About Us

LipimetiX Development was established as a joint venture between Capstone Therapeutics Corp. (OTCQB: CAPS), and LipimetiX, LLC

We are a privately held biopharmaceutical company created to develop a class of drugs to treat refractory hypercholesterolemia, coronary artery, and peripheral artery diseases by rapidly decreasing arterial cholesterol content and inflammation. LipimetiX's technology is based upon small peptide mimetics of Apolipoprotein E, a critical protein that directs cholesterol and triglyceride rich lipoproteins to receptors on the liver. LipimetiX's lead peptide, AEM-28, is currently being developed for genetically induced refractory hypercholesterolemia, an orphan indication that leads to early cardiovascular disease. AEM-28 has been granted orphan drug designation from the FDA.